Naturecol's line of omega 3 fatty acids include high concentrations of EPA/DHA for brain and heart health. 90% concentrations formulated in all natural fish capsules and a   fish gelatin seal. As a powerful anti-inflammatory agent EPA    is used as an adjunct therapy for Arthritis, Osteoporosis, and Osteoarthritis.This EPA formulation is the purest on the     market with levels of over 1,000 mgs of EPA per serving.

What problems can an Ultra Pure Omega-3 EPA fish oil help?

Extensive clinical studies over the past thirty years using omega-3 fish oil suggest that it can be used to successfully treat a wide range of illnesses including:

·         Depression

·         low moods

·         lack of concentration

·         attention-deficit-hyperactivity disorder              
     (ADHD or ADD)

·         bipolar disorder

·         obsessive-compulsive disorder (OCD)

·         rheumatoid arthritis

·         osteoporosis

·         inflammation & joint problems

·         cholesterol and blood pressure

·         many heart conditions

·         blurry vision

·         and promote youthful healthy skin and hair.

How Pure EPA fish oil works?

Your brain is 60% fat ( Watch the video on pregnancy ). So to keep your mind healthy, your diet must contain Omega-3 EPA/DHA essential fatty acids which your brain and body can only get from fish. Omega-3 fatty acids make up an enormous 10% of the average human brain. So you won’t be surprised to hear that omega-3 oil, obtained from fish, has been shown to be particularly effective in keeping your mind healthy.

Fish oil is no miracle cure, rather it feeds your body essential nutrients that it needs. It helps your system deal with any imbalances you may have, so it radically improves your overall health (mental and physical).

If you have already tried fish oil and have been disappointed by the results, it’s very likely that you were taking standard fish oil, rather than the clinical grade oil that was actually used in the scientific research.

Fish oil of this clinical strength cannot be found in health food stores or pharmacies.

Naturecol now provides its Ultra Pure EPA/DHA and soon to come Ultra Pure DHA/EPA that is needed to provide therapeutic benefits. Naturecol molecularly distills it's fish oil “3” times which gives it a water clear pure grade that has not been seen before.

How much do I need to take?

Articles and other worldwide media sources have repeatedly shown that the recommended daily dose of a high grade Omega-3 EPA is 1 gram or 1000mgs EPA fish oil, daily (in the strength of Naturecol’s Omega-3 EPA/DHA) in order to get clinical benefits.

Benefits of taking Pure EPA.

Your way of life will change for the better. You will start to see to the major benefits that have been so well documented over the years. Extensive clinical studies over the past thirty years using omega-3 fish oil suggest that it can be used to successfully treat a wide range of illnesses including:

Depression, low moods, lack of concentration, attention-deficit-hyperactivity disorder (ADHD or ADD), bipolar disorder, obsessive-compulsive disorder (OCD), rheumatoid arthritis, osteoporosis, inflammation & joint problems. It can also lower cholesterol and blood pressure, is good for the heart, and promote youthful healthy skin and hair.

EPA to DHA.

Naturecol’s Omega-3 EPA/DHA contains ultra-pure EPA, 7/1 ratio.

Each Naturecol EPA/DHA capsule contains over 500 mgs of ultra-pure EPA. It is the purest (and arguably the most effective) EPA fish oil supplement on the world market.

Both EPA and DHA are essential fatty acids that you can only obtain from fish. Articles and other worldwide media sources have repeatedly shown that the recommended daily dose of a high grade Omega-3 EPA is 1 gram or 1000mgs EPA fish oil, daily (in the strength of Naturecol’s Omega-3 EPA) in order to get clinical benefits.

What else is unique about Naturecol's E PA/DHA.

Each capsule of Naturecol’s Omega-3 EPA/DHA is made under strict cGMP conditions, with “all natural” capsules and molecularly distilled “3” times to produce a water clear pure fish oil that the public has not yet seen.

Where does EPA come from?

What is EPA?

EPA is short for (eicosapentaenoic acid). It is a nutrient extracted from omega-3 fatty acids, which are the good fats found in oily fish such as sardines, salmon and mackerel.

Essential to life and good health, omega-3 EPA, is believed to be of particular importance for eye and brain function.

How does EPA work?

One area of study shows that low levels of EPA are associated with a slowing of brain activity, owing to a hardening of the phospholipid layers, which slow cell signaling. This decreased communication between brain cells can lead to symptoms of depression and other brain imbalances.

Taking EPA can reverse this harmful process by increasing the amount of phospholipids in brain-cell membranes. This has a positive effect on neurotransmitters and enhances electrical messaging in the brain.

Can’t I just eat fish?

Taking a daily dose of Naturecol’s Omega-3 EPA can be more reliable than having to make sure you regularly eat the right amount of the right kind of fish.

Many types of fish now contain traces of toxic metals such as mercury, lead and even arsenic. Many “standard” fish oils do too. Naturecol’s purification process, Puremax, removes these toxins from the fish oil, making it an ideal safe way to get your daily dose of these valuable nutrients.

Heart Health

It's now estimated that individuals with a higher dietary intake of EPA and DHA reduce their risk of heart disease by roughly 47% compared to those individuals who do not eat fish.

The essential fatty acids in fish oil, known as omega-3s (mainly EPA and DHA), not only are important for a healthy heart and the cardiovascular system, but play a critical role in the health of your skin, joints, cell membrane structure, nervous system, fight depression and make kids smarter.

When researchers measured the level of the omega-3 fatty acids EPA and DHA within red blood cells, they found that they had discovered one of the most significant predictors of heart disease called the omega-3 index. 

This index was a better predictor of coronary heart disease than other established markers such as total, LDL, or HDL cholesterol; C-reactive protein; and homocystiene. A low omega-3 index score resulted in the least protection and the greatest score resulted in the most protection. The omega-3 index for those individuals with the greatest protection consumed the equivalent of 1,000 mg of EPA and DHA a day. Most experts recommend a daily dosage of 1,000 mg of EPA and DHA combined. Higher doses may be required for therapeutic applications.

Arthritis is characterized by symptoms which include inflammation, painful joints and stiffness.  Rheumatoid arthritis is a chronic auto-immune disease that is extremely painful and can lead to severe disability. Osteoarthritis can be described as wear and tear of the joints with a resulting loss of cartilage.

Numerous studies have found that fish oil can improve the symptoms of rheumatoid arthritis by significantly reducing inflammation and in some cases, even lessen the need for non-steroidal anti-inflammatory drugs. Similarly with osteoarthritis, studies have found that fish oil suppresses the action of cartilage destroying enzymes.

Fish oil contains the essential Omega 3 fatty acids that are found in oily fish such as Salmon, Tuna, Sardines and Mackerel. They are essential in that the body cannot  produce them itself. We can only source them from our diet. Most of us simply do not get enough Omega 3 fatty acids.

Traditionally, man ate a diet that was rich in omega-3s but now, our diet is low in omega-3s. There is a substantial amount of research indicating that it is this imbalance of Omega 3's in our diet that are mainly responsible for the higher incidence of inflammatory diseases, cancers and allergies that we see today.

The Omega 6 fatty acids are also essential, but are easy to obtain, they can be found in cooking oils, such as corn oil and sunflower oil, and in processed foods and convenience foods. They promote inflammation in the body and help the blood to clot.  The Omega 3's do exactly the opposite; they have anti-inflammatory properties and help to thin the blood.

Clinical trials have reported that after taking fish oil for 3 months, patients found that their symptoms of arthritis improved, with less inflammation, pain and stiffness.  Furthermore, those taking fish oil for longer than 3 months found they had an increase in grip strength.

As there is some evidence that Rheumatoid Arthritis is the result of oxidative stress on the body, and fish oil is an antioxidant, it is particularly important to choose a high quality fish oil containing a powerful antioxidant such as vitamin E.

Pregnancy

If you want to ensure that you and your child are healthy and happy during and after pregnancy, consistent supplementation with omega-3 can help. A recent controversy has been widely reported over whether or not it is safe for women to eat fish during pregnancy. A group of scientists have released a study showing that the benefits to moms and babies taking omega-3s found in fish far outweigh the risks associated with ingesting the mercury and other contaminants in fish. Even still you want to be sure to take no chances with your baby. Pregnant women can get all of the benefits of omega-3 from fish, without taking any risks. With Naturecol’s high purity Omega-3 EPA/DHA you can be sure that there are no toxins to worry about. Our Omega-3 has been distilled three times to produce the purest form of water clear, pure Omega-3’s that you can buy.

Omega-3 is Dr. Recommended

I strongly advise those pregnant and nursing women who choose not to eat fish to be certain to take supplementary [omega-3] DHA. Fatty fish are high in DHA, which is good, but they are often high in toxic metals and environmental contaminants that are particularly damaging to babies.
-John Robbins, Author of Food Revolution

“In the last month of pregnancy and first month of neonatal life, omega-3 fatty acids are rapidly incorporated into the brain of the baby.”

Andrew Weil, M.D., Author of 8 Weeks to Optimum Health and Ask Dr. Weil

“The [omega-3] EPA of oily fish or fish oil supplements assist development of the fetal brain. They prolong gestation and increase birth weight.”

-  Thomas Bartram, Author of Bartram’s Encyclopedia of Herbal Medicine

“[Omega-3] DHA plays a particularly crucial role in the brain development of infants and children.  DHA accumulates in the fetal brain late in pregnancy, and continues to accumulate during an infant's first few months of life.  Researchers have determined that [omega-3] fatty acids affect intelligence in infancy and perhaps later in life.”
-   Dr. Julian Whitaker, Author of The Memory Solution

“Omega-3 fatty acids are essential for the normal development of the unborn baby's brain, especially during the final three months of gestation when the size of its brain increases threefold. If the mother fails to get enough of these nutrients in her diet, the fetus will pirate what she has stored in her tissues—including her brain.  Lab tests show that new mothers have half the normal blood levels of omega-3 fatty acids.  Women who breast-feed their babies have even lower levels of DHA because they are continuing to supply the baby's need for omega-3 fatty acids.  If a woman does not replenish her store of these essential elements following the birth of a child, she will have lower and lower levels with each additional child.  Some people suggest this is why firstborn children score higher on intelligence tests. Until now, people have attributed the well documented mental superiority of firstborn children to the fact they spend more one on one time with a parent.  It is now being suggested that their greater cognitive abilities may also be due to a more generous supply of maternal DHA."

Nature's Anti-depressant: 

EPA is part of the Omega-3 chain of ecosanoids and is most commonly found in fatty fish such as fresh salmon, mackerel, and sardines. Over the years the diet patterns of most people in the west has shifted dramatically to include far more hydrogenated oils and Trans fats    (bad fats). This is largely due to the increased consumption of fast food. Even people who think they eat a healthy diet consume way too much omega 6 and not enough omega 3.

Researchers have recently found that a diet high in Trans fats could affect the mood stabilizing hormones within the brain, this is thought to be due to the saturated fats slowing down the messaging system within the brain, should this happen then the onset of depression could occur.

As well as EPA being very good for helping to balance mood it has other well documented effects:

·        Blood thinning properties*

·          Decrease risk of heart attack*

·           lowers blood pressure*  

There is also some limited scientific evidence to show that high grade EPA has helped people suffering from:-

·          Bipolar disorder*

·          Obsessive compulsive disorder*

·          Schizophrenia*

·          ADHD*

·          ADD*

Although more research needs to be done in these areas, the current evidence looks very promising.

Since Dr Malcolm Peet, a consultant psychiatrist at Sheffield swallow court hospital released his findings about the effects of Ethyl EPA and its effects on people suffering from depression and low moods, many other studies have been performed using Ethyl EPA to help treat depression and related disorders. The vast majority of the studies that have been performed consistently confirmed that Ethyl EPA, a natural substance found in omega 3 fish oil, helps relieve depression and low moods. 

Relatively high doses of EPA appear to be required to achieve significant benefits in neurodevelopment disorders. Naturecol's omega-3, as a high purity, high potency EPA concentrate, offers a child-friendly solution for effective supplementation. It allows effective doses to be given in smaller, moor child-friendly capsules.
 

DHA/EPA and Brain Development

A growing number of studies in human infants is showing a strong correlation between the intake of omega-3 oils, especially DHA, and cognitive function, visual acuity, and overall brain development. human infant brain development undergoes its most rapid and complex growth during the last trimester of pregnancy and the first two years after birth. This means that during this period the child’s neurological development is highly dependent on its dietary intake of essential nutrients, especially omega-3 oils.
Because the fetal and infant brain is unable to convert  alpha-linolenic oil (an omega-3 oil) into DHA, the baby  depends on its mother for its supply. Lipids make up 50 to 60% of the structure of the brain, with DHA making up 30% of the brain and 50% of the retina’s structure. However, since the baby depends on the mother for its supply of DHA, omega-3 deficiencies can lead to deficiency in the infant brain with each successive birth. Studies have shown that brain DHA deficiency is limited to about 30% with the first generation, but by the third generation, brain DHA levels can fall by as much as 85%. 
The average DHA and EPA intake combined in the USA is about 100-200 mgs/day, far below the 650 mgs of DHA and 1000 mgs EPA that experts recommend for healthy individuals. Furthermore, it has been shown that after birth, DHA levels fall between the ages of 6 and 12 months mostly due to low DHA content in most baby foods and formulas, which can have a profound effect on postnatal brain development. A study that measured the impact of DHA on visual development in 6 month old infants found that retinal and visual cortex maturation was greatly improved in infants receiving DHA versus control infants who were deficient in DHA.  
In developing babies, higher levels of DHA levels are needed for the growth of neuronal cells and other brain structures. The composition of the membranes of neural cells is under constant reconstruction, and can change drastically with changes in diet. It has been shown that while other fatty acids plateau at birth, DHA levels actually double, mainly during periods of intense nerve cell development, that is, during intense brain growth. Overwhelming evidence for the benefits of DHA comes from a recent review of some 50 studies, which concluded that higher DHA in babies’ diets translates into better brain function, especially for cognitive and visual function. Further evidence that DHA may promote healthy nervous system development comes from a recent study in which researchers divided normal, healthy infants into two groups. One group was bottle fed with a DHA formula and the other group bottle fed with a formula containing no DHA. Using assessments of visual, auditory, and sensory perception, they found definite abnormalities in all three tests in the bottle fed babies at one year of age.

A devastating consequence of low DHA status is its impact on the development of neurological abnormalities. In another study, researchers measured DHA, essential fatty acids, trans fatty acids, and arachidonic acid levels in the umbilical artery and vein of infants. They found that infants with neurological abnormalities at birth had significantly lower levels of arachidonic acid and DHA and higher trans fatty acid levels. In contrast, infants with higher arachidonic acid, DHA, and essential fatty acid levels had more normal neurological function. In a further test of cognitive development in infancy, researchers found that maternal and fetal DHA levels measured at birth correlated with attention and distractibility at 12 and 18 months, with those having higher DHA levels better than those with low levels.  

DHA and the Adult Brain
While DHA is essential for the proper development of the infant brain, it also plays a vital role in the ongoing structure and function of the adult brain. It is a component of several important phospholipids in the brain, with the highest levels of DHA being found in phosphatidylethanolamine (PE) and phosphatidyl-serine (PS). Lower levels exist in phosphatidyl-cholines (PC). Structurally, DHA comprises 22 carbons and six double bonds, making it the most unsaturated fatty acid in cell membranes and an important ingredient in increasing the fluidity of cell membranes. 
Changing the fluidity of cell membranes alters their physical properties, such as permeability and protein activity. This change can drastically alter cell signaling and plays a major role in increasing membrane permeability of cancer cells, making them more susceptible to immunologic and chemothera-peutic killing. EPA, however, has much less effect on membrane fluidity than DHA.
It has also been shown that a greater incorporation of DHA into cell membranes results in dramatically less susceptibility to lipid peroxidation and oxidative stress in cells, especially neurons. 
Although many view the brain as a stable structure that changes little after adolescence, it is in fact always in a state of flux, not only by forming millions of new nerve connections, but also by replacing and altering its biochemical makeup, especially membrane lipids. Connected with this constant turnover of brain lipids are the phospholipase enzymes, which can release arachidonic acid and DHA from the cell membrane. Dietary changes can therefore drastically alter brain lipids, which can significantly alter brain function, even worsening neuropsychiatric disorders. 
Furthermore, there is evidence that as we age, the distribution of DHA in the brain changes. For example, during infancy the highest levels are found in the striatum (associated with motor control) and are lower in the hypothalamus (linking the nervous and endocrine systems) and hippocampus (associated with memory). In adults, the highest levels are in the cortex (essential to cognition) and lowest in the medulla (crucial for autonomic function). With aging, the highest levels are in the cortex and cerebellum (involved in motor control). An example of this regional specificity was seen in a recent study when scientists restored dietary DHA to rats that had been deprived of the nutrient. They found that all areas of brain DHA were restored after 12 weeks, except for the medulla, which recovered only 62% of its DHA.41 These findings therefore provide plentiful evidence that consuming enough DHA may be essential for upkeep of the adult brain.

Fish oil nutrition and babies: Fish oil contains two important Omega-3 fatty acids called EPA and DHA. EPA and DHA are needed for brain development. They occur together in nature and human cells, and should be taken in this natural tandem form.

DHA (docosahexaenoic acid) is a polyunsaturated fatty acid found in deep-sea cold water fish. DHA is an essential nutrient for proper brain, nervous system, and visual function and must be obtained through the diet. A healthy balance of DHA is essential to properly care for the brain throughout life, particularly during the early stages of development.

A high concentration of DHA can be found in mother's breast milk. However, the level is directly related to the amount of Omega-3 fatty acids that are consumed in the mother's diet. Due to refined foods and trendy diets, many individuals have reduced their intake of the dietary sources of Omega-3 fatty acids, contributing to lower levels of DHA in breast milk. The impact of low DHA intake on neurological function of adults and children is the subject of ongoing clinical investigations.

Naturecol’s Omeaga-3 fatty acids are pharmaceutical grade, molecularly distilled, and third party tested to document the absence of all environmental pollutants (No PCBs, dioxins, pesticides or heavy metals).

Suggested Use & Recommended Intake

INFANTS (1–18 months) 0–15 lbs

* One Capsule EPA/DHA

CHILDREN (1.5–5 yrs)

* One Capsule EPA/DHA

ADULTS (6–100 yrs)

* Two Capsules EPA/DHA

Warning: Consult with your physician before using this product if you are pregnant, diabetic, allergic to iodine, using blood thinners, or anticipate surgery. Keep out of the reach of children.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Omega 3 Ultra high purity EPA (ecosapentaenoic acid) concentrate 

Ultra high purity EPA (ecosapentaenoic acid) concentrate. Naturecol provides the highest concentrations of EPA required to produce therapeutic benefits. Our water clear, pure formulation  ( 7:1 ratio of EPA:DHA ) is essential for brain function such as cell signaling and neuronal blood flow* Increases learning ability*, problem-solving skills*, focus and memory*Structural role in neuronal membranes and is crucial for early visual, neuronal and brain development*, for growing infants, before and after birth*  Improves mood *  Supports healthy nervous, immune system function* Promotes healthy youthful skin and hair* Supports weight loss and sugar balance* Relieves and prevents inflammation and minor pain* Promotes joint health *Promotes cardiovascular health* Reduces triglycerides and supports healthy cholesterol*. 

Naturecol provides the highest concentrations of EPA ( 7:1 ratio of EPA:DHA ) required to produce therapeutic benefits.   

• Brain cell signaling and neuronal blood flow*
• Increases learning ability, problem solving skills, focus and memory*
• Structural role in neuronal membranes and crucial for early visual, neuronal and brain development, for growing infants, before and after birth*
• Improves mood*
• Promotes healthy youthful skin and hair*
• Supports weight loss and sugar balance*
• Supports healthy nervous, immune system function*
• Promotes joint health*
• Relieves and prevents inflammation and minor pain*
• Promotes cardiovascular health*
• Reduces triglycerides and supports healthy cholesterol blood thinning properties*
• Decrease risk of heart attack*
• Decrease growth rate of atherosclerotic plaque*
• Decrease blood pressure*

How Does EPA Work? 
 
While the benefits of high grade EPA have been well documented, the scientific community still don't know exactly how EPA works on the brain, one theory released by Dr Basant Puri is that it eases the passage of the signals over the tiny gaps in the brain called synapses. Another theory was that  high Grade EPA actually worked similar to lithium and had anti depressant properties of its own. 
 
Until recently it was widely accepted in the medical community that once a human reached maturity that the adult brain could not grow anymore, in a recent paper just released by Dr Puri his findings show other wise. Dr Puri scanned a 21 year patient before treating him with high grade Pure EPA, after the course of treatment he rescanned the young man only to find that the gray matter of the brain had increased in size. 

Learning and Concentration

Neurodevelopment disorders such as attention-deficit hyperactivity disorder (ADHD), developmental coordination disorder (DCD) and dyslexia show a high degree of clinical overlap. All are associated with essential fatty acid (EFA) deficiencies or imbalances.

The supplementation effect of long chain polyunsaturated fatty acids such as ultra pure omega-3 EPA:DHA  has been evaluated on children with diagnosed DCD, many of whom had ADHD-related symptoms, behavior and learning difficulties. In these double blind clinical trials, the active treatment was a daily dose of 558mg EPA and 174mg DHA . An olive oil supplement was the placebo. Within just 3 months, the active treatment group made highly significant improvements in nearly all behavioral scales, including the three diagnostic features of ADHD: inattention, hyperactivity and impulsivity. This group also saw significant improvements in reading, spelling and short-term memory, compared to the placebo group.